Lydia Maigne, PHD¹, Paul De Vlieger, Phd, Student¹, Lemlih Ouchchane, MD, PhD², Laurent Gerbaud Sr., MD/PHD³, Aline Guttmann, MD, MSc², David Manset, MPhil⁴, Jean-Yves Boire, MD/PHD² and Vincent Breton, PHD¹, 1Clermont University, University Blaise Pascal, CNRS/IN2P3, UMR 6533, LPC, Aubière, France, 2School of Medicine, Auvergne University, Clermont-Ferrand, France, 3Service de Santé publique, Université d'Auvergne, Clermont-ferrand, France, 4Biomedical Applications, MAAT France, Archamps, France