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Tuesday, March 6, 2007 - 9:05 AM
27

Will Pediatricians Adopt the New Rotavirus Vaccine?

Allison Kempe1, Matthew F. Daley2, Umesh D. Parashar3, Lori A. Crane4, Brenda L. Beaty5, Shannon Stokley6, Jennifer Barrow5, Christine Babbel5, L. Miriam Dickinson7, Marc-Alain Widdowson8, James P. Alexander3, and Stephen Berman1. (1) Dept. of Pediatrics, Univ. of Colo. HSC, Children's Outcomes Research Program, The Children's Hospital, 1056 E. 19th Avenue, Denver, CO, USA, (2) Department of Pediatrics & the Children's Outcomes Research Program, Children's Outcomes Research Program, The Children's Hospital, 1056 E. 19th Avenue, B032, Denver, CO, USA, (3) Centers for Disease Control and Prevention, Atlanta, GA, USA, (4) Preventive Medicine & Biometrics, University of Colorado Health Sciences Center, 4200 E 9th Ave, Box B-119, Denver, CO, USA, (5) Colorado Health Outcomes Program, University of Colorado Health Sciences Center, 12477 East 19th Ave., Box F443, Aurora, CO, USA, (6) National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, MS E-52, Atlanta, GA, USA, (7) Dept. of Family Medicine, University of Colorado Health Sciences Center, 4200 E 9th Ave, Box B-119, Denver, CO, USA, (8) Epidemiology Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA


Learning Objectives for this Presentation:
By the end of the presentation participants will be able to describe pediatricians' intentions to recommend the new rotavirus vaccine and perceived barriers to its use.

Background:
In February 2006, the FDA announced the approval of a new rotavirus vaccine.

Objectives:
To determine among pediatricians: 1) perceptions regarding the need for a rotavirus vaccine; 2) intentions for recommending the newly licensed vaccine; 3) perceived barriers to implementation; and 4) factors associated with plans for vaccine adoption.

Methods:
A nationally representative network of 431 pediatricians was surveyed by internet or mail during January and February 2006, prior to licensure of the rotavirus vaccine. The survey summarized results of the new rotavirus vaccine trial and asked about intentions to use the vaccine and anticipated barriers.

Results:
Survey response rate was 71% (N=305). Of the respondents, 52% strongly agreed and 37% somewhat agreed with the need for a rotavirus vaccine. If recommended for routine use, 50% would strongly recommend and 34% would recommend but not strongly; 52% would begin to use within 6 months. The top 3 “definite” barriers to implementation included concerns about uniform coverage of vaccine by insurers (52%), lack of adequate reimbursement (42%), and parental reluctance because of withdrawal of previous rotavirus vaccine (26%). In multivariate analysis, factors associated with very likely adoption of the vaccine included perception of a high burden of rotavirus infection and a high level of confidence in pre-licensure studies of vaccine safety. Physician concerns about safety of the new vaccine and the perception of parental concerns about vaccine safety in general were negatively associated with adoption.

Conclusions:
The majority of pediatricians reported willingness to implement the new rotavirus vaccine, most within 6 months. Major barriers to optimal implementation included provider concerns about reimbursement issues and parental acceptance of the vaccine.

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