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Tuesday, March 6, 2007 - 9:20 AM
25

Replacement of Td with Tdap in Michigan in 2006, measured using the MCIR

Kyle S. Enger, Division of Immunization, Michigan Department of Community Health, 201 Townsend St, Lansing, MI, USA


Learning Objectives for this Presentation:
By the end of the presentation participants will be able to describe patterns in the use of Td and Tdap in Michigan.

Background:
Tdap resembles Td, but boosts immunity to pertussis in addition to tetanus and diphtheria. Tdap was FDA-approved in mid-2005 and ACIP-recommended in March 2006. Although few adolescents received it before the 2005-2006 school year, substantial uptake was expected before the 2006-2007 school year. A Td booster is required for Michigan students if 10+ years have passed since the last tetanus or diphtheria vaccination.

Objectives:
Determine to what extent Tdap is replacing Td in Michigan.

Methods:
The Michigan Care Improvement Registry (MCIR) provided records of Td-containing vaccinations since 1997 on 12 Oct. 2006; they were charted by year of vaccination, vaccine type, and age at vaccination.

Results:
Td administration peaked every August since 1997 (except during the 2001 Td shortage). In 2006, the percentage of Td-containing vaccines that were Tdap increased steadily from 34% in January, leveling off at ~78% in August and later months. For the 12-month period ending in mid-Oct., 134,929 Td-containing vaccines were recorded (similar to Michigan's birth cohort of ~130,000). Of these, 4.5% were in children < 11y, 36% in children 11-12y, and 59.5% in persons > 12y (similar to the previous 4 years). 69.5% of Td-containing vaccinations in children aged 11-12y were Tdap, compared to 54.5% for persons > 12y. However, coverage with Td & Tdap remained low (e.g., 19% of persons aged 11-12y on 12 Oct. 2006 had 1+ Td-containing vaccines recorded).

Conclusions:
More Tdap than Td was reported in Michigan in 2006. This is a promising sign for pertussis control efforts. Reporting to MCIR of Td-containing vaccines should be improved.