Background: Vaccination programs in schools and organized childcare centers can play an important role in increasing coverage rates for some vaccines among children and adolescents. In 2009, the Task Force on Community Preventive Services updated their evidence-based findings regarding the use of these interventions.
Objectives: To update a prior systematic review of the evidence on effectiveness of vaccination programs in schools and organized childcare centers for increasing vaccination rates and in reducing morbidity and mortality among children and adolescents.
Methods: The prior review was updated with a systematic search for the period 1998–2009. Intervention studies and economic evaluations were abstracted, and findings were summarized and translated into conclusions on effectiveness and economic efficiency according to Community Guide methods and rules of evidence.
Results: Eighteen new studies were added for a total body of evidence of 29 intervention studies for the period 1980–2009. Of these, 16 studies (19 study arms) provided a common measurement of change in vaccination rates with a median absolute percentage increase of 41 percentage points (Interquartile Interval
Conclusions: Based on Community Guide rules of evidence, there is strong evidence that vaccination programs in schools and organized childcare centers are effective in improving vaccination rates among children and adolescents for a range of vaccines. Programs in these settings may be most useful for new vaccines and vaccines with new, expanded recommendations.
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