Background: With successful canine rabies control programs implemented in most Latin American countries, vampire bats have emerged as the most important reservoir responsible for regular outbreaks and human deaths in the
Setting: Various public health settings, including local and national level, clinics, outreach, and educational settings.
Population: Indigenous people and new immigrants to the Amazon region for natural resource exploitation, such as logging, mining and farming.
Project Description: Potential solutions to the problem are proposed and discussed: 1) Use of intradermal vaccination schedules; 2) Consideration of reduced vaccination schedules; 3) Opportunities for single dose vaccination for boosters, and enhanced pre-exposure vaccination in highly endemic areas; 4) Applied research on modern recombinant and genetically modified vaccines. Each potential solution is described regarding efficiency, relevance, and perspectives for future availability.
Results/Lessons Learned: The urgency for application of proven PEP strategies, such as intradermal vaccination, and trials for novel rabies vaccines is proposed. Stakeholders in Amazon countries need to be engaged to develop more efficient and realistic solutions for these neglected populations.