Obesity and the related risks for diseases and morbidity represent a serious public health threat with significant costs, especially for young people, families, and communities. Among African American and Hispanic populations, particularly among the young, the rates of obesity are far greater than in other groups. Spot the Block is an Food and Drug Administration (FDA) campaign designed to teach tweens, along with their families, how to use the Nutrition Facts Label as a way to make more informed and healthy decisions about their diets. The campaign is a multiyear effort using strategies that have proven highly successful in other behavior change health programs and includes a public–private partnership between FDA and Cartoon Network, community educators, media, and interactive Web outreach. Speakers on this panel will address effective social marketing efforts that encourage individuals, in particular African American and Hispanic populations, to read and use the Nutrition Facts Label to make better dietary choices that ultimately affect their health.