Will Gonorrhea Become XDR-GC?

With the recent loss of fluoroquinolones as recommended treatment for gonococcal infections, the only remaining class of drugs still recommended and available is the cephalosporins. Reports of clinical treatment failures to some of the oral cephalosporins have been identified in the Far East. The Gonococcal Isolate Surveillance Project (GISP), the national sentinel surveillance system which monitors antimicrobial susceptibilities of Neisseria. Gonorrhoeae, has become an increasingly important source of information. This presentation will describe the current antimicrobial resistance trends seen in GISP and address the challenges of monitoring for the emergence of cephalosporin-resistant gonorrhea in the US.