Start | Browse by Day | Author Index | Browse Handouts

A3.1 Risk Factors Associated with Trichomonas Vaginalis Infection As Measured with a Nucleic Acid Amplification Test In Women In the United States

Tuesday, March 13, 2012: 10:15 AM
Regency
Charlotte Gaydos, DrPH, School of Medicine, Division of Infectious Diseases, STD Laboratory, Johns Hopkins University, Baltimore, MD, Christine Ginocchio, PhD, Department of Pathology and Laboratory Medicine, North Shore-LIJ Health System Laboratories, Lake Success, NY, Lake Success, NY, Kimberle C. Chapin, MD, Department of Pathology, Rhode Island Hospital, Providence, RI, Jennifer Smith, PhD, Epidemiology, University Of North Carolina, Chapel Hill, NC, Jaber Aslanzadeh, PhD, ABMM, Microbiology, Clinical Lab Partners and Harford Hospital, Newington, CT, Janet Snook, BS, Product Training & Applications, Gen-Probe, Inc, San Diego, CA and Craig Hill, PhD, Infectious Diseases, Gen-Probe, Inc, San Diego, CA

     

Background: Since Trichomonas vaginalis (TV) infections are not reportable, prevalence of infection in the U.S. is not well characterized. Prevalence and risk factor studies have been limited by use of insensitive methods and banked retrospective samples.

Objectives: To determine TV prevalence and risk factors for infection in the U. S. among women undergoing screening for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC).

Methods: Samples from 7,593 women (18-89 years old) undergoing routine CT and GC screening in various clinical settings in 21 states were collected.  Samples previously tested for CT and GC by the APTIMA Combo 2® Assay (AC2, Gen-Probe) were tested using the APTIMA Trichomonas vaginalis Assay (ATV, Gen-Probe Inc.).  Samples consisted of endocervical swab, urine, vaginal swab, and PreservCyt liquid Pap samples. Risk factors for infection were analyzed by logistic multivariate analysis.

Results: Overall prevalence of TV, CT, and GC was 8.7%, 6.7%, and 1.7%, respectively.   Highest TV prevalence was in women aged >40 yr. (>11%), while highest CT and GC prevalence was in women <30 yr.  TV prevalence differed by race/ethnicity (20.2% Blacks; 5.7% Whites; 5.0% Hispanics; 3.8% Asians).  TV prevalence ranged from 5.4% in samples collected at Family Planning clinics to 22.3% for samples collected from women in jails. Risk factors for infection included age > 40 yr. (OR 1.5); Black Race (OR 4.0); being screened in the Emergency department/inpatient (OR 3.5); screening in jail/STD clinic (OR 2.6); living in the Southeast (OR 6.3); Southwest (OR 1.9); and Midwest (OR2.0); compared to living in the Northeast.

Conclusions: TV prevalence is highest in women >40 years, which is an independent risk factor for infection. Other highly significant risk factors include Black Race and living in the southeast.

Implications for Programs, Policy, and Research: Clinicians should screen older women for trichomonas as well as those at highest risk of infection.

See more of: The “Have Nots” Have and the “Haves” Have Not: Inequalities and STDs In the United States
See more of: Oral and Poster
Previous Abstract | Next Abstract >>