Background: Human papillomavirus (HPV) vaccine is recommended routinely for all adolescents (females since 2006; males since 2011). STD clinic populations are at higher risk of HPV infection and could benefit from HPV vaccination. We calculated missed opportunities for vaccination throughout New York City (NYC) among STD clinic attendees.
Methods: We matched medical record data for adolescents attending NYC STD clinics during 2010-2013 against the Citywide Immunization Registry (CIR), which contains all immunization records for NYC residents aged ≤18 years. Analysis was limited to patients who had ≥1 immunization event in CIR between 1/1/2008-12/31/2013 (females) and 1/1/2012-12/31/2013 (males) at which time patients were 11-18 years old and eligible for HPV vaccine. We used logistic models to examine associations between a missed opportunity, defined as occasions when patients received another vaccine in any healthcare setting and were eligible for, but did not receive HPV vaccine, and race/ethnicity, census-tract poverty, number of sex partners, and history of STD.
Results: Overall, 57.0% (4,321/7,586) of females and 48.6% (461/948) of males had ≥1 missed opportunity. Missed opportunities did not differ by race or poverty-level among males, but non-Hispanic (NH) females were significantly more likely to have a missed opportunity compared with Hispanics (NH-Black: OR=1.5, 95% CI: 1.4-1.7; NH-White: OR=1.6, 95% CI: 1.3-1.9; NH-Other: OR=1.9, 95% CI: 1.4-2.6), and females living in lower-poverty census tracts were more likely to have missed opportunities (versus very-high-poverty, high-poverty: OR=1.3, 95% CI: 1.2-1.5; medium-poverty: OR=1.4, 95% CI: 1.2-1.5; low-poverty: OR=1.6, 95% CI: 1.4-1.9). Numbers of sex partners and STD history were not associated with ≥1 missed opportunity.
Conclusions: Adolescents attending STD clinics had evidence of missed opportunities for HPV vaccination. Providing HPV vaccine in STD clinics, along with other efforts to increase the recommendation/administration of HPV vaccine in primary care, could improve citywide HPV vaccination coverage.