important role in many areas of public health. This session will explore these issues in service to STD prevention. The first presentation focuses on how nutrition, injury and cancer prevention have long recognized the important role that industries play as a determinant of health and have addressed them through a variety of strategies. It also explores how STD prevention can do the same, and what role science and policy can play in addressing industries such as dating sites and apps, alcohol, and the adult film industry. The second presentation explores the value of STD screening relative to other evidence based preventive services to help make the case for appropriate financial and human resource support for continuing, expanding and starting STD screening programs and policies. Using simulation modeling, the science of STD screening is translated into estimates of their population health impact and cost-effectiveness. Consistent estimation methods were applied to a wide range of evidence-based preventive services to create a valid ranking of relative value. The ranking facilitates comparison of the value of STD preventive services to other widely recognized and commonly delivered preventive care. Finally, the third presentation highlights how the science of HIV has resulted in powerful tools for prevention – sensitive, rapid tests for HIV, simplified treatment regimens to hasten and maintain viral suppression and effective drug regimens for Pre- and Post-exposure prophylaxis. These tools have enabled NY City and State to develop policy and fund population-based programming aimed at ending the HIV Epidemic. One major investment has been to transform the STD clinical care paradigm from one of provider of last resort for episodic care, to destination clinics which function as hubs of sexual health care including the full spectrum of HIV and other sexual health services.