More than 64% of women are prescribed medicines during pregnancy. Many women take medicines for chronic conditions like diabetes, hypertension, and depression which may start or get worse during pregnancy. Pregnant women and new mothers also have to make complex decisions about which foods and other products are safe for themselves and their babies. Half of Americans go online for health information. Pregnant women frequently turn to the internet and social media for tips and videos on pregnancy. The FDA Office of Women’s Health has web-based and print resources to connect women to information on the safe use of medicines, devices and foods during pregnancy and breastfeeding. FDA has established partnerships with USA.gov and text4baby - the National Healthy Mothers, Healthy Babies Coalition to conduct innovative digital and print campaigns to provide pregnant women and new moms with science-based, reliable information on a variety of topics critical to maternal and child health, including nutrition and medication use. Text4baby is the nation’s first free health text messaging service for pregnant women, and USA.gov serves as a portal to connect the public with free materials available from the federal government. The proposed panel will outline successful strategies for targeting pregnant women through digital campaigns and print publication promotions. Panel presentations will describe outcomes and lessons learned from FDA’s collaborations with text4baby and USA.gov.