This session highlights APHL findings on consolidated and shared IT services models, possible impacts on the laboratory, and barriers to collaboration such as unique terminologies and business processes. One state will provide their experience with the mandated electronic submission of reportable laboratory results, and how the lack of standards at the time hampered their implementation, and how they overcame this problem. The third presentation will describe a business model for harmonization of Electronic Laboratory Data Exchange (ELDE) across public health by describing a composition of network, business platform for data exchange, use cases and approaches for building model-driven tools.