This presentation will discuss the utilization of grid technology to implement an information sharing system that enables interoperability between different health surveillance systems. The proposed information sharing implementation provides a service that operates in a secure framework that is independent of the local surveillance system interface and transparent to the community of users on the grid. The information sharing tool will also implement a user interface for those officials not participating on the grid. The JHUAPL Center of Excellence is developing a prototype information sharing system that will operate on a Public Health Grid. This system will utilize a Public Health Grid to enable communication between different jurisdictions using diverse health surveillance systems. JHUAPL will also conduct a simulated exercise to evaluate the benefits of the information sharing prototype. Results and lessons learned from the exercise will be discussed. A demonstration of the Information Sharing system will also be presented.