WP 175 Prevalence of Chlamydia Trachomatis Infection in Women Aged 14-25 Years: A Simulation Based Screening Program in the Brazilian Amazon Region

Tuesday, June 10, 2014
International Ballroom
Camila H A Bôtto de Menezes, Camila Bôtto-Menezes1, Nina Schwartz Benzaken, Nina Benzaken2, Lucilia de Fátima Santana Jardim, Lucília Jardim3, Dária Barroso Serrão das Neves, Dária Neves4, André L Leturiondo, André Leturiondo3, Daniel L Rodrigues Dutra, Daniel Dutra3, Cynthia de Oliveira Ferreira, Cynthia Ferreira3, Sergio Souza da Cunha, Sergio Cunha5 and Adele Schwartz Benzaken, Adele Benzaken6, 1Universidade do Estado do Amazonas (UEA), Universidade Federal do Amazonas (UFAM), Manaus, Brazil, 2Universidade Nilton Lins (UNL), Manaus, Brazil, 3Fundação Alfredo da Matta (FUAM), Manaus, Brazil, 4Universidade do Estado do Amazonas, Universidade Federal do Amazonas, Manaus, Brazil, 5Fundação Alfredo da Matta (FUAM) Universidade Federal de Pernambuco (UFPE), Manaus, Brazil, 6Universidade Nilton Lins (UNL), Fundação Alfredo da Matta (FUAM), National STD/Aids and Viral Hepatitis Department, Manaus, Brazil

Background: According to the World Health Organization (WHO), Chlamydia trachomatis(Ct) is the most prevalent bacterial sexually transmitted infection (STI). It is usually asymptomatic and it can lead to pelvic inflammatory disease and infertility in women with untreated Ct infection. Although chlamydia screening programs undertaken in a range of countries since 2005, and Ct test by hybrid capture is available by Brazilian Health System, there is no screening program or a simple screening strategy for sexually active youngers women in Brazil. The present abstract aims to estimate the prevalence of Ct infection in female users of primary health service without STI symptoms in Manaus.

Methods: A based screening program was simulated in 22 health clinics of primary public health service in women aged 14-25 years, from an urban area of Manaus in the Amazonas state. After women were given informed consent, they were interviewed about demographic and sexual behavior characteristics. A pelvic examination was performed using Papanicolau test and endocervical swabs specimens were collected for use in the Ct test by health workers. Testing for Ct was carried out by hybrid capture/DIGENE (HC2 CT-ID DNA Test, Version 2.0, Qiagen) at Fundação Alfredo da Matta.

Results: From October 2012 to October 2013, 1196 women were tested for current Ct infection. The prevalence of Ct infection was 12.4% (145/1165).

Conclusions: The results presented here are preliminary but until the moment the prevalence of Ct infection was superior to those found in the same area in 2005 which the prevalence for pregnant women (asymptomatic control group) and women with sexually transmitted disease (STD) were 11.9% and 10%, respectively. Active detection of infection and early treatment are crucial strategies to detect people with an asymptomatic infection and to reduce the transmission, the sequels in terms of reproductive morbidity and the cost for tertiary care service.