The 1946-48 Guatemala STI Clinical Studies -Ethical and Public Health Implications

Zenilman, Jonathan

Thursday, March 15, 2012: 8:30 AM-10:15 AM

Nicollet Grand Ballroom (A/B)

Background/Purpose:

In 1946-48, the USPHS conducted human subject studies on STDs in Guatamala. Review by historians and by the US Presidential Commission on Bioethical Issues have uncovered important ethical concerns

Objectives of Symposium:

To review the scientific rationale for these studies in time relevant context

Describe the experiments and populations studied

Frame the bioethical questions resulting from this research

Implications for Programs, Policy, and Research:

The Guatemala experience provides a cautionary tale for human subject experimentation and for public health research on vulnerable populations. There are profound implications for assuring that human subject safety is paramount, and the need for ethical review.

8:30 AM

D1.1

The USPHS Studies in Guatemala--Background, Scientific Questions, and What Happened

Jonathan Zenilman, MD, Division of Infectious Diseases, Johns Hopkins University, Baltimore, MD

8:50 AM

D1.2

The Presidential Commission for the Study of Bioethical Issues--Roles and Responsibilities

Valerie Bonham, JD, Presidential Commission for the Study of Bioethical Issues, Washington, DC, Andorra

9:10 AM

D1.3

Historical and Contextual Perspectives of the Guatemala Studies

Paul Lombardo, JD, Ph.D, School of Law, Georgia State University, Atlanta, GA

9:30 AM

D1.4

Ethical Approach and Implications of the Guatemala STI Studies

Dan Sulmasy, MD, PhD, Schools of Medicine and Divinity, University of Chicago, Chicago, IL

9:50 AM

D1.5

Response From the American STD Association

Bradley Stoner, MD, PhD, Washington University School of Medicine, St. Louis, MO

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D1 The 1946-48 Guatemala STI Clinical Studies -Ethical and Public Health Implications